Position Description:
One or more full time postdoctoral positions are available immediately for highly motivated postdoctoral scholars interested in vascular or neural mechanisms in blood pressure control related to hypertension in the laboratory of Dr. Curt D. Sigmund in the Department of Physiology at the Medical College of Wisconsin. A qualified candidate for this position is expected to have a strong publication record and excellent references from PhD or postdoctoral research. A notable feature of this postdoctoral fellowship will be experience in combining state-of-the-art genetic and molecular methods (including CRISPR-Cas9 genome editing) with sophisticated physiologic techniques to address fundamental mechanisms of vascular and neural function in genetically modified mouse models in hypertension. Proficiency in physiology or pharmacology and experience with genetics and molecular biology is highly desired. Potential project includes: 1) examining genomic interactions regulating PPAR target gene expression in vascular smooth muscle and endothelium, 2) physiological, and proteomic analysis of Cullin-3 adaptors and substrates in vascular smooth muscle and endothelium, and 3) relative role of angiotensin II receptor G protein and -arrestin signaling related to fluid homeostasis, metabolic function and blood pressure. The successful applicants can be expected to use sophisticated tools in physiological genomics utilizing cell and primary culture, and organ and whole mouse physiology. They will work in a multidisciplinary team with a diversity of interests, ideas, and experiences. Full time postdoctoral positions available immediately for highly motivated postdoctoral scholars interested in vascular or neural mechanisms in blood pressure control related to hypertension in the laboratory of Dr. Curt D. Sigmund in the Department of Physiology at the Medical College of Wisconsin. A qualified candidate for this position is expected to have a strong publication record and excellent references from PhD or postdoctoral research. A notable feature of this postdoctoral fellowship will be experience in combining state-of-the-art genetic and molecular methods (including CRISPR-Cas9 genome editing) with sophisticated physiologic techniques to address fundamental mechanisms of vascular and neural function in genetically modified mouse models in hypertension. Proficiency in physiology or pharmacology and experience with genetics and molecular biology is highly desired. Potential project includes: 1) examining genomic interactions regulating PPAR target gene expression in vascular smooth muscle and endothelium, 2) physiological, and proteomic analysis of Cullin-3 adaptors and substrates in vascular smooth muscle and endothelium, and 3) relative role of angiotensin II receptor G protein and -arrestin signaling related to fluid homeostasis, metabolic function and blood pressure. The successful applicants can be expected to use sophisticated tools in physiological genomics utilizing cell and primary culture, and organ and whole mouse physiology. They will work in a multidisciplinary team with a diversity of interests, ideas, and experiences. To post your application, please click here to apply or at Medical College of Wisconsin Careers: Requisition #28135. You will need to upload a single PDF attachment containing 1) a cover letter indicating your research interests, 2) CV including list of all publications, and 3) list of 3 or more references who can be immediately contacted without further permission. Characteristics of a postdoctoral appointment: It is expected that postdocs at MCW, with the assistance of their supervisor, will: Primary Functions
Preferred Schedule:
Monday-Friday; 8:00 am - 5:00 pm
Position Requirements:
Knowledge - Skills - Abilities Required knowledge: biology, chemistry, mathematics, statistics, documentation, records management, data utilization, complex problem solving, critical thinking, resource management, and writing skills Specifications Minimum Required Education: PhD in a scientific field or MD Minimum Required Experience: None,
Preferred Experience: Experience in physiology or pharmacology and with genetics and molecular biology
MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination
The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.
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